Neonatal Intensive Care Drug Manual




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Dosage / Interval


Pertussis – post-exposure prophylaxis and treatment1 (azithromycin is recommended. Use erythromycin only if azithromycin is not available).

10 mg/kg/dose PO 6-hourly for 5 to 14 days; 14 days preferred to avoid risk of relapse.


Chlamydia infection (conjunctivitis, pneumonia)

12.5 mg/kg/dose PO 6-hourly for 14 days.2


Non-chlamydial, susceptible bacterial infection in penicillin-allergic infants3

Weight <1 kg:

-Postnatal age ≤14 days: 10 mg/kg/dose 12-hourly

-Postnatal age >14 days: 10 mg/kg/dose 8-hourly


Weight ≥1 kg:

-Postnatal age ≤7 days: 10 mg/kg/dose 12-hourly

-Postnatal age >7 days: 10 mg/kg/dose 8-hourly
Prokinetic dose for gastrointestinal dysmotility (inconsistent evidence for its efficacy and safety and routine use not recommended)

Low-dose regimens: 2.5 mg/kg/dose 6-hourly up to 10 days.10 or 5 mg/kg/dose 8-hourly (7–14 days)11

High dose regimens: Doses up to 10–12.5 mg/kg/dose 6-hourly for 7–14 days have been used.12-14

Post-op intestinal atresia: 3 mg/kg/dose 6-hourly19



Route

Oral


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Neonatal Intensive Care Drug Manual

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