Neonatal Intensive Care Drug Manual




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Pancreatic Enzymes/Creon


Revision Date : 30 December 2020

Approved: LM, KOH




Indication :

Pancreatic enzyme replacement or supplementation for conditions of pancreatic enzyme insufficiency. E.g. cystic fibrosis.

Dose :

Different brands of enzyme products are available. All contain lipase, amylase and protease. The dose is expressed in units of lipase and is titrated to control steatorrhoea. If on full feeds start with 5,000 units/kg/day and increase if necessary. Use a lower dose if on partial feeds. Consult a Gastroenterologist before diciding on a product and dose.

Interval :

Divide total daily dose between each feed, so that some is given with every feed

Route :

Orally.


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Neonatal Intensive Care Drug Manual

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