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Neonatal Intensive Care Drug Manual
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| bet | 98/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Calcitriol
Revision Date : 23-12-2020
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Approved : TC, KOH
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Indication :
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Hypocalcemia
Hypoparathyroidism
Neonatal Rickets
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Dose :
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Initial, 0.25 mcg to 1 mcg orally. Increase by 0.25microgram every 4 weeks according to Calcium levels Adjust dose to maintain serum calcium in the lower range
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Interval :
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Once daily
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Route :
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Oral
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Total Daily Dose :
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N/A
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Comments :
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The most active form of Vitamin D. Hypercalcaemia is a danger and the dosage should be adjusted to avoid intoxication. Regular monitoring of serum calcium, phosphate and ALP is necessary. Symptoms of hypercalcemia include lethargy, weakness, ectopic calcification, constipation, polyuria and weight loss.
Can be administered at anytime with regards to feeds
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Supplied as :
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Oral solution: 1microg/mL available on SAS (Special Access Scheme)
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Dilution :
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Not required. Remove fluid from capsule with syringe and administer orally.
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Stability :
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Use immediately.
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Storage :
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Protect from light. Store below 25degree celsius
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Incompatibility :
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Not Applicable.
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Serum Levels :
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N/A.
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References
Takemoto CK, Hodding JH, Kraus DM. Pediatric & neonatal dosage handbook with international trade names index : a universal resource for clinicians treating pediatric and neonatal patients. 24th ed. Hudson (Ohio): Lexicomp; 2019. 2,401.
Truven Health Analytics. Calcitriol. In: NeoFax [Internet]. Greenwood Village (CO): Truven Health Analytics; 2020 [cited 23-12-20]. Available from: https://neofax.micromedexsolutions.com/
Australian Medicines Handbook. Calcitriol. In: Australian Medicines Handbook [Internet]. Adelaide (South Australia): Australian Medicines Handbook; 2020 [cited 23-12-2020]. Available from: https://amhonline.amh.net.au/
Original version Date: 9/1/2014
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Author: AK, JD
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Current Version number: 2
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Version Date: 23/12/2020
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Risk Rating: Medium
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Due for Review: 23/12/2025
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Approval by: DTC
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Approval Date: TBA
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