Neonatal Intensive Care Drug Manual




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Dosage / Interval


0.5 mL IM.

Should be given to all infants as soon as possible after birth.


The greatest benefit is seen when the first dose is administered within 24 hours.
The first dose must be given within 7 days.
A total of four doses should be administered at either:
− Birth, 2 months, 4 months and 6 months OR
− Birth, 2 months, 4 months and 12 months

Babies born at < 32 weeks gestation or with a birth weight < 2000 g, are recommended to have their vaccine given at 0, 2, 4 and 6 months of age and either:


− Measure hepatitis B antibodies at 7 months of age and give a booster at 12 months of age if antibody titre is < 10 mUnits/mL OR
− Give a booster at 12 months without measuring antibody titre.

Record details of vaccination in patient's Personal Health Record ('Blue Book') and complete Australian Community Immunisation Register records and complete a NSW Neonatal Hepatitis B Vaccination Program Form.

Record vaccine batch number on the medication chart.



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Neonatal Intensive Care Drug Manual

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