Neonatal tetany/convulsions

An RCT of oral calcium gluconate versus oral phenobarbitone versus MgSO4 0.2 mL/kg (100 mg/kg) of 50% magnesium sulfate IMI in infants with hypocalcaemic convulsions secondary to feeding with full-cream evaporated milk reported infants treated with magnesium sulphate had higher plasma-calcium concentrations after 48 hours’ treatment and fewer convulsions during and after the treatment period. (LOE II GOR C/D) Magnesium levels increased from 0.59 +/- 0.17 mmol/L pretreatment to 0.87 +/- 0.2 mmol/L post treatment.