Neonatal Intensive Care Drug Manual

The manifestations of -blocker overdose include bradycardia, atrioventricular (AV)blockade, hypotension, left ventricular failure and cardiogenic shock.

Common (>1%) adverse reactions include bradycardia, hypotension, orthostatic

hypotension, transient worsening of heart failure (when treatment starts), nausea, diarrhoea, bronchospasm, dyspnoea, cold extremities, exacerbation of Raynaud’s phenomenon, fatigue, dizziness, abnormal vision, alteration of glucose and lipid metabolism.

Avoid too fast up-titration.

Hemangiol Oral Solution: Use within 2 months of opening.

Compounded suspension from Pharmacy Department: Shelf life usually 30 days. Refer to expiry on bottle.

Auspman Oral Solution: Store below 30°C.

Hemangiol Oral Solution: Store below 30°C. Do not freeze. Protect from light.

Compounded suspension from Pharmacy Department: Refrigerate or store according to instructions on bottle.