Neonatal Intensive Care Drug Manual

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  Severe bradycardia, arrhythmias and cardiac arrest.
  
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  Patients who are hypovolaemic may become hypotensive.
  
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  In situations where other vasodilators or negative chronotropic agents are administered, co-administration of dexmedetomidine could have an additive pharmacodynamic effect causing hypotension and bradycardia.
  
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  Bradycardia and hypotension may be potentiated when dexmedetomidine is used concurrently with propofol or midazolam.
  
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  Nausea, fever, vomiting, hypoxia and anaemia.
  
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  Hypothermia.
  
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  Seizures.
  

Adrenaline (epinephrine), alfentanil, amikacin, aminophylline, amiodarone, amphotericin B liposome, ampicillin, azithromycin, aztreonam, calcium gluconate, cefazolin, cefepime, cefotaxime, cefoxitin, ceftazidime, ceftriaxone, ciprofloxacin, cisatracurium, clindamycin, dexamethasone, digoxin, dobutamine, dolasetron, dopamine, droperidol, ephedrine sulfate, erythromycin, esmolol, fentanyl, fluconazole, furosemide (frusemide), gentamicin, glyceryl trinitrate, glycopyrronium bromide (glycopyrrolate), heparin, hydromorphone, ketamine, lidocaine (lignocaine), linezolid, magnesium sulfate, methylprednisolone sodium succinate, metoclopramide, metronidazole, midazolam, milrinone, morphine, naloxone, noradrenaline (norepinephrine), pancuronium, paracetamol, piperacillin-tazobactam (EDTA-free), phenobarbital (phenobarbitone0, potassium chloride, promethazine, propofol, ranitidine, remifentanil, rocuronium, sodium bicarbonate, sodium nitroprusside, suxamethonium, thiopental sodium, tobramycin, trimethoprim-sulfamethoxazole, vancomycin, vecuronium, verapamil.