Neonatal Intensive Care Drug Manual




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Flecainide


Revision Date : 12-01-2021

Approved : TC, KOH




Alert

Use in consultation with a Paediatric Cardiologist.

Contraindicated in infants with reduced myocardial contractility.

Use caution in patients with congenital heart disease—increased potential for pro-arrhythmic effects.

Intravenous flecainide needs close cardiorespiratory monitoring



Indication

Treatment of paroxysmal supraventricular tachycardia, paroxysmal atrial fibrillation/flutter and life- threatening ventricular dysrhythmias as a second-line agent where tachycardia has been resistant to first-line agents.

Action

Decreases intracardiac conduction for all parts of the heart, with the greatest effect in the His-Purkinje system. It acts by blocking fast sodium channels. As a type Ic agent, it slows cardiac conduction and decreases contractility.

Drug type

Type Ic antiarrhythmic agent.

Trade name

Flecainide Sandoz Tablets; Flecatab Tablets; Tambocor solution for injection, Tambocor Tablets


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Neonatal Intensive Care Drug Manual

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