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Neonatal Intensive Care Drug Manual
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| bet | 21/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Dosage / Interval
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Dose range 0.1 to 0.3 mg/kg
The initial recommended dose is 0.1 mg/kg but if AV block is not achieved within 2 minutes, further doses should be increased by 0.1 mg/kg aliquots to a maximum of 0.3 mg/kg.
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Maximum daily dose
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The first dose should not exceed 6 mg and the second dose 12 mg. [1] If multiple doses are required within 24 hours, consult cardiologist to discuss further management.
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Route
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Intravenous
Successful intraosseous administration has been reported.
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Preparation/Dilution
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Draw up 1 mL (3 mg) and add 9 mL sodium chloride 0.9% to make a final volume of 10mL with a concentration of 0.3 mg/mL.
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Administration
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Intravenous, as proximally as possible, as a rapid IV bolus followed by a rapid flush of sodium chloride 0.9%. Use of filter may slow down infusion.
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Monitoring
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Adenosine should be used only where cardiac monitoring and cardiorespiratory resuscitation equipment is available for immediate use if necessary.
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