Concurrent use of immunoglobulin and live virus vaccines may result in interference with the immune response to the live vaccine. The Australian Technical Advisory Group on Immunisation (ATAGI) recommendations are below:
Hepatitis B vaccine is an inactivated vaccine and can be administered at any time before, after or concurrently with IVIg.
Rotavirus vaccine may be administered at any time before, after or concurrently with any blood product, including antibody-containing products.
BCG vaccine can be given at any time before or after administration of immunoglobulin or any antibody-containing blood product.
Following the receipt of IVIg for ITP treatment, an interval of 8–10 months should elapse before vaccination with an MMR, MMRV or varicella vaccine.
May result in false-positive Coombs test due to passive transmission of antibodies to erythrocyte antigens.
May result in a falsely elevated blood glucose measurement due to assay interference with the glucose dehydrogenase (pyrroloquinoline-quinone) method.
| 