|
Lignocaine for local anaesthetic, cardiac arrhythmia
|
bet | 337/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
Revision Date : 01/03/2021
|
Approved: DT, TC, KOH
|
Indication :
|
Ventricular arrythmias
Local anaesthesia
Topical anaesthesia
|
Dose :
|
Ventricular arrythmias: 1 mg/kg (0.1 ml/kg of 1%) loading dose. Follow within 15 minutes with an infusion of 10-50 microg/kg/min otherwise repeat loading dose if infusion delayed >15 minutes.
Local anaesthesia: maximum dose without adrenaline 5 mg/kg
Surface (Topical) anaesthesia: of mouth, throat and upper GI tract: mixture up to 3 mg (0.15 ml)/kg/dose
|
Interval :
|
Loading dose can be repeated within 15 minutes if infusion not started
Local anaesthesia: do not repeat
Topical: do not repeat within 2 hours
|
Route :
|
IV over 2 minutes
Local infiltration
Topical, can dab onto severe mouth ulcers before feeds
|
Total Daily Dose :
|
1) As per requirements for Arrhythmias
2 and 3) As per interval above
|
Comments :
|
Can give 1% undiluted or dilute with NS. Excessive topical use in mouth can paralyse gag reflex.
|
Supplied as :
|
1% ampoules (10mg/ml)
Mixture: 2% Xylocaine Viscous
Gel: 2%
|
Dilution :
|
For IV infusion using 1% lignocaine solution (10mg/ml) take 3 ml multiplied by weight of the patient in kg and make up to 50 ml with NS. 1 ml/hr = 10 microg/kg/min. DO NOT USE THIS DILUTION FOR SEIZURE PROTOCOL
|
Stability :
|
Discard any remaining solution from ampoules – intended for single use only.
|
Storage :
|
Room temperature.
|
Incompatibility :
|
Thiopentone, Phenytoin, Ampicillin, Acyclovir, Phenobarbitone
|
Compatibility:
|
5% Dextrose, N/2 Saline, NS, aminophylline, calcium gluconate, digoxin, dobutamine, dopamine, adrenaline, frusemide, heparin, hydrocortisone, insulin, nitroglycerine, KCl, ranitidine.
|
Serum Levels :
|
Lignocaine levels are not performed at TCH. If required they can be sent away to RNS, ring specimen referrals on 42845. Levels above 9mg/L are associated with cardiac toxicity in adults, but there is little information regarding levels in neonates.
|
Original version Date: 2014
|
Author: DT
|
Current Version number: 2
|
Version Date: 1-3-2021
|
Risk Rating: Low
|
Due for Review: 1-3-2025
|
Approved by: DTC
|
Approval Date: TBA
|
|
| |