• CAUTION: Infants on prolonged opioid infusion may develop acute withdrawal following naloxone Maximum dose
  • Neonatal Intensive Care Drug Manual




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    Dosage / Interval


    1. At birth – newborn infants with respiratory depression secondary to maternal opioid administration 100 microgram/kg. Repeat dose as required.

    DO NOT USE IN INFANTS BORN TO MOTHERS SUSPECTED OR KNOWN TO BE ADDICTED TO OPIOIDS.
    2. Reversal of opioid-induced respiratory depression 10–100 microgram/kg. Repeat dose as required.

    CAUTION: Infants on prolonged opioid infusion may develop acute withdrawal following naloxone


    Maximum dose

    2mg

    Route



    Intravenous (IV) injection preferred. IM suitable if the IV route is not available. Alternate routes: intraosseous and subcutaneous.,



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    Neonatal Intensive Care Drug Manual

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