• Contraindications
  • Drug Interactions
  • Neonatal Intensive Care Drug Manual




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    Preparation/Dilution

    400 microgram/mL

    Administration


    Use undiluted.

    Intravenous (IV) bolus at proximal cannula site.

    Intramuscular (IM).


    Monitoring

    Continuous cardiorespiratory monitoring is required.

    Resuscitation facilities must be readily available.




    Contraindications


    Naloxone is contraindicated in persons known to be hypersensitive to it.


    Precautions

    Naloxone should not be administered to babies whose mothers are known or suspected to be addicted to opioids.

    The duration of action of naloxone is short, particularly after intravenous administration and subsequent observation of the infant should be instituted.




    Drug Interactions

    Naloxone reverses the analgesic and other effects of opioid agonists.


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    Neonatal Intensive Care Drug Manual

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