Neonatal Intensive Care Drug Manual




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Contraindications


Infants with hypovolaemia until blood volume replaced - may cause severe peripheral and visceral vasoconstriction.

Infants with mesenteric or peripheral thrombosis.

Known hypersensitivity to sodium metabisulfite.


Precautions

Use with caution in preterm infants and infants with poor myocardial contractility as a sole inotrope/vasopressor.

Thyrotoxicosis – may cause severe hypertension.

Ensure adequate circulating blood volume prior to commencement.
Avoid in hypertension.

Overdosage may result in severe hypertension, reflex bradycardia, marked increase in peripheral resistance and decreased cardiac output.

The infusion site should be checked frequently for free flow. Care should be taken to avoid extravasation into the tissues which may cause local necrosis.

Do not cease infusion abruptly.




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Neonatal Intensive Care Drug Manual

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