• Compatibility
  • Neonatal Intensive Care Drug Manual




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    Drug Interactions

    Should be given with close monitoring to patients exposed to monoamine oxidase inhibitors because severe, prolonged hypertension may result.

    Adverse Reactions


    Systemic hypertension especially at higher doses.

    Reflex bradycardia and arrhythmia.

    Tissue necrosis at infusion site with extravasation. [see special comments]

    Renal and digital ischaemia may occur.

    Prolonged administration of any potent vasopressor may result in plasma volume depletion which should be continuously corrected by appropriate fluid and electrolyte replacement therapy.


    Compatibility


    Fluids: Glucose 5%, sodium chloride 0.9% with glucose 5%, sodium chloride 0.9%, lactated Ringer’s solution.
    Y-site: Amiodarone, anidulafungin, bivalirudin, caspofungin, ceftaroline fosamil, cisatracurium, dexmedetomidine, dobutamine, dopamine, doripenem, esmolol, ethanol, haloperidol lactate, heparin sodium, hydrocortisone sodium succinate, labetalol, midazolam, milrinone, morphine sulfate, mycophenolate mofetil, potassium chloride, remifentanil, sodium nitroprusside, tigecycline.


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    Neonatal Intensive Care Drug Manual

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