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Neonatal Intensive Care Drug Manual
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bet | 396/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
Drug Interactions
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Should be given with close monitoring to patients exposed to monoamine oxidase inhibitors because severe, prolonged hypertension may result.
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Adverse Reactions
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Systemic hypertension especially at higher doses.
Reflex bradycardia and arrhythmia.
Tissue necrosis at infusion site with extravasation. [see special comments]
Renal and digital ischaemia may occur.
Prolonged administration of any potent vasopressor may result in plasma volume depletion which should be continuously corrected by appropriate fluid and electrolyte replacement therapy.
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Compatibility
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Fluids: Glucose 5%, sodium chloride 0.9% with glucose 5%, sodium chloride 0.9%, lactated Ringer’s solution.
Y-site: Amiodarone, anidulafungin, bivalirudin, caspofungin, ceftaroline fosamil, cisatracurium, dexmedetomidine, dobutamine, dopamine, doripenem, esmolol, ethanol, haloperidol lactate, heparin sodium, hydrocortisone sodium succinate, labetalol, midazolam, milrinone, morphine sulfate, mycophenolate mofetil, potassium chloride, remifentanil, sodium nitroprusside, tigecycline.
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