• Administration IV bolus: Administer dose over at least 5 minutes. Monitoring
  • Contraindications
  • Neonatal Intensive Care Drug Manual




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    Continuous infusion

    Use the 50 mg/2 mL injection (Zantac) for IV infusion: Draw up 0.2 mL/kg (5 mg/kg of ranitidine) and make up to 50 mL with sodium chloride 0.9%, glucose 5% or glucose 10%. Infuse at a rate of 1 mL/hour = 100 microg/kg/hour


    Ranitidine Sandoz 50 mg/5 mL injection has no stability data at room temperature and therefore not recommended for IV infusion.

    Administration

    IV bolus: Administer dose over at least 5 minutes.

    Monitoring

    Nil

    Contraindications

    Patients with known hypersensitivity to any component of the preparation.

    Precautions

    Caution should be observed in patients with hepatic dysfunction since ranitidine is metabolised by the liver. Ranitidine is excreted via the kidneys. In the presence of severe renal impairment, plasma concentrations of ranitidine are increased and elimination prolonged. Bradycardia — ensure recommended rates of administration as not exceeded.


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    Neonatal Intensive Care Drug Manual

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