Neonatal Intensive Care Drug Manual

Term neonate — 1.5 mg/kg/dose every 8 hours

Preterm (< 37 weeks) neonate — 0.5 mg/kg/dose every 12 hours
Continuous IV infusion: 30–60 micrograms/kg/hour²²

Administer undiluted.

CAUTION: There are two vial concentrations available.

If using the 50 mg/2 mL injection draw up 1 mL (25 mg of ranitidine) and add 9mL of sodium chloride 0.9%, glucose 5% or glucose 10% to make a final volume of 10mL with a concentration of 2.5 mg/mL solution.
If using 50 mg/5 mL injection, draw up 2.5 mL (25 mg of ranitidine) and add 7.5mL of sodium chloride 0.9%, glucose 5% or glucose 10% to make a final volume of 10mL with a concentration of 2.5 mg/mL solution.