• Drug interactions Not applicable Adverse reactions
  • Compatibility Not applicable Incompatibility
  • Storage Store below 30°C. Excipients
  • Neonatal Intensive Care Drug Manual




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    Contraindications

    Resonium A and Calcium Resonium should not be administered orally to neonates and is contraindicated in neonates with reduced gut motility (e.g. post-operatively or drug induced).(2)

    History of hypersensitivity to polystyrene sulfonate resins.

    Serum potassium levels less than 5 mmol/L.

    Obstructive bowel disease.



    Precautions

    Hypercalcaemia, hyperparathyroidism: avoid calcium resin.

    Congestive heart failure, hypernatraemia, sodium overload: avoid sodium resin



    Drug interactions

    Not applicable

    Adverse reactions

    Electrolyte imbalances: Hypokalaemia, hypernatraemia, hypocalcaemia, hypercalcaemia, hypomagnesaemia

    Water overload

    Gastrointestinal: Perforation, haemorrhage, necrotising enterocolitis


    Compatibility

    Not applicable

    Incompatibility

    Not applicable

    Stability

    Suspensions of the resin should be freshly prepared and not stored beyond 24 hours.

    Once reconstituted, Resonium A and Calcium Resonium is a cream to light brown coloured suspension in which small white particulates may remain visible.



    Storage

    Store below 30°C.

    Excipients

    Resonium A and Calcium Resonium: Saccharin sodium and vanillin.


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    Neonatal Intensive Care Drug Manual

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