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Neonatal Intensive Care Drug Manual
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| bet | 534/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Dose
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Dose: 1 g/kg every 4 hours, followed by colonic irrigation 8-12hours later (see Administration section)
Type of resin:
Resonium A: if plasma sodium is normal or if plasma calcium is high.
Calcium Resonium: if plasma sodium is high
Duration of therapy: Cease once serum potassium returns to normal (<6 mmol/L)
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Dose adjustment
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No specific information.
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Maximum dose
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Total cumulative dose
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Route
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Rectal
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Preparation
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Dilute each gram/kg of Resonium with 3-5mL/kg of Water for Injection or glucose 10%.
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Administration
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PR only, should not be administered orally
Aim to retain dose rectally for as long as possible, at least 30 minutes.
Evacuation of resin: Evacuate Resonium 8-12 hours later with glycerine enema or 1 to 2 mL of sodium chloride 0.9%.
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Monitoring
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Serum electrolytes: potassium, sodium, calcium (hypercalcaemia) and magnesium (hypomagnesaemia).
Cardiorespiratory and apnoea monitoring
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