Neonatal Intensive Care Drug Manual

4–5 microgram/kg over 20 minutes.

Monitor serum potassium and heart rate (tachycardia) closely. If potassium critical or continues to rise, consider repeating dose every 4 hours9 or use of other strategy (insulin/glucose; addition of, rectal cation-resin).
Inhalation:

400 microgram via nebulisation. Repeat two-hourly as required and titrated to response [serum, potassium or respiratory status] and heart rate [tachycardia].

Draw up 0.4 mL (200 microgram of salbutamol) and add 19.6 mL of water for injection to make a 10 microgram/mL solution.

Draw up 1 mL/kg of the above solution (10 microgram/kg of salbutamol) and add to water for injection to make a final volume of 10mL with a final concentration of 1 microgram/kg/mL.

Draw up 0.4 mL (400 micrograms of salbutamol) from the 1 mg/mL inhalation ampoule and add 1.6 mL sodium chloride 0.9% to make a final volume of 2 mL with a final concentration of 0.2mg/mL.

Draw up 0.2 mL (400 micrograms of salbutamol) from the 2 mg/mL inhalation ampoule and add 1.8 mL sodium chloride 0.9% to make a final volume of 2 mL with a final concentration of 0.2mg/mL.