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Neonatal Intensive Care Drug Manual
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| bet | 596/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Adverse Reactions
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Uncommon.
Too high a replacement dose can cause manifestations of thyrotoxicosis.
Overtreatment with levothyroxine may cause craniosynostosis, accelerated growth and maturation, disturbed sleep patterns and effects on temperament. There can also be behavioural problems (social withdrawal, hyperactivity, conduct problems and anxiety) in children treated with initial starting doses of levothyroxine >10 microgram/kg/day. Overtreatment should be avoided by careful monitoring. [2]
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Compatibility
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Not applicable.
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Incompatibility
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Not applicable.
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Stability
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Tablets: discard unused portion.
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Storage
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Eutroxsig and Oroxine tablets: Store at 2–8°C. Tablets may be stored below 25°C for up to 14 days. Please refer to special comments section for further details. Protect from light.
Eltroxin tablets: Store below 25°C. Protect from light.
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