Ketamine – Concurrent use may result in marked hypertension and tachycardia.
Glucocorticoids – can decrease serum thyroglobulin concentration, affect deiodinase activity, decrease TSH secretion.
Ferrous sulphate, calcium carbonate, PPIs, H2 blockers and bile acid sequestrants can affect levothyroxine absorption.
Phenytoin, phenobarbital, carbamazepine – can affect thyroid hormone metabolism therefore increasing levothyroxine requirements.
Dopamine, dobutamine, growth hormone – can decrease TSH secretion
Radioiodine contrast agents and topical iodine application: may lead to transient hypothyroidism associated with low free T4, low free T3 and variable TSH (the Wolff–Chaikoff effect).[3-5]
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