Neonatal Intensive Care Drug Manual




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Cephazolin


Revision Date : 16-12-2020

Approved: TC, KOH




Alert

High risk medicine. The Antimicrobial Stewardship Team recommends this drug is listed under the following category: Unrestricted.

Contains 48 mg of sodium per gram of cefazolin sodium.



Indication

Treatment of infections caused by susceptible organisms:

  • Gram positive bacteria Streptococci and Staphylococci including beta-lactamase producing Staphylococci

  • Gram negative bacteria Escherichia coli and some Klebsiella specie, provided these are reported susceptible to cefazolin).

Action

Bactericidal. Inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin binding proteins.

Drug type

Antibiotic, First generation cephalosporin.

Trade name

Cefazolin Sandoz, Cefazolin-AFT, Hospira Cefazolin, Kefzol, Cephazolin Alphapharm


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Neonatal Intensive Care Drug Manual

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