Neonatal abstinence syndrome




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Sana03.01.2022
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Neonatal abstinence syndrome: The optimal regimen to manage symptomatic NAS is unclear. [15] In infants with NAS secondary to opioid withdrawal, clonidine 5 microgram/kg/day up to a maximum 12 microgram/kg/day in 6-8 divided doses may reduce need for morphine treatment and duration of treatment. [7] [LOE II, GOR C]

Sedation: Evidence is insufficient to show the efficacy and safety of clonidine for sedation and analgesia in term and preterm newborn infants receiving mechanical ventilation. [8] [LOE II GOR D]


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