Term neonate (37+0 weeks and over)
PO: Loading dose of 10 microgram/kg/dose 8-hourly for 3 doses, followed by
Maintenance dose of 8 microgram/kg/dose daily (may increase up to 12 microgram/kg/day according to therapeutic drug monitoring and in consultation with cardiologist)
IV: Loading and maintenance doses are 75% of oral dose.
Preterm neonate:
PO: Loading dose of 10 microgram/kg/dose 8-hourly for 3 doses, followed by
Maintenance dose of 5–7.5 microgram/kg/dose daily (up to 12 microgram/kg/day according to therapeutic monitoring and in consultation with cardiologist)
IV: Loading and maintenance doses are 75% of oral dose.
| 