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Neonatal Intensive Care Drug Manual
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| bet | 227/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Evidence summary
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Efficacy:
Heart failure: Controlled trials have demonstrated diuretics increase urinary sodium excretion and decrease physical signs of fluid retention in patients with HF. In short-term studies, diuretic therapy led to a reduction in jugular venous pressures, pulmonary congestion, peripheral oedema and body weight; all of which were observed within days of initiation of therapy. In intermediate-term studies, diuretics have been shown to improve cardiac function, symptoms and exercise tolerance in patients with HF. There have been no long-term studies of diuretic therapy in HF and thus, their effects on morbidity and mortality are not known.2
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