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Neonatal Intensive Care Drug Manual
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| bet | 224/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Drug Interactions
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Furosemide can cause the depletion of potassium and magnesium, which can predispose patients to serious cardiac arrhythmias, particularly in the presence of digitalis therapy.
The risk of electrolyte depletion is markedly enhanced when 2 diuretics are used in combination.
May prolong action of muscle relaxants.
Avoid concomitant usage of aminoglycosides to avoid ototoxicity.
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Adverse Reactions
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Furosemide is associated with renal losses of calcium, sodium, chloride and potassium.
Prolonged and higher doses of furosemide are associated with ototoxicity and nephrocalcinosis.
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Compatibility
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Fluids: Glucose 5%, glucose 10%, glucose 20%, sodium chloride 0.9%
Y-site: Amifostine, amikacin, anidulafungin, aztreonam, bivalirudin, ceftaroline fosamil, dexmedetomidine, doripenem, foscarnet, granisetron, heparin sodium, hydrocortisone sodium succinate, levosimendan, linezolid, lorazepam, metoprolol, piperacillin-tazobactam (EDTA-free), potassium chloride, remifentanil, sodium nitroprusside, tirofiban, tobramycin.
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