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Neonatal Intensive Care Drug Manual
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| bet | 32/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Albumin 4%
Revision Date : 18-02-2021
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Approved : TC,KOH
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Alert
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Albumex® 4 is normally clear or slightly opalescent. If it appears to be turbid, it must not be used and the bottle should be returned unopened to the Australian Red Cross Blood Service.
Albumin is not recommended as the initial resuscitating fluid in hypotensive infants.
If the product has been stored in the refrigerator it should be allowed to reach room temperature before administration.
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Indication
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Hypovolaemia/shock with or without hypoalbuminaemia
Plasma exchange [normal saline recommended]
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Action
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Albumin is involved in the maintenance of colloid osmotic pressure, binding and transport of plasma compounds (bilirubin, bile acids, long-chain fatty acids, thyroxine, vitamin D, calcium, magnesium, copper, zinc), renders some potential toxins harmless, is a carrier of nitric oxide and affects pharmacokinetics of many drugs. Albumin 4% is approximately isotonic with osmolality 260 mOsm/kg and pH 6.7 to 7.3. The half-life of albumin is about 19 days.
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Drug Type
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Plasma product, manufactured from human plasma collected by the Australian Red Cross Blood Service.
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