Adverse Reactions
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Tachycardia and arrhythmia.
Systemic hypertension and lactic acidosis especially at higher doses.
Tissue ischaemia and necrosis especially if administered intra-arterially, intramuscularly or with
extravasation.
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Compatibility
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Fluids: Glucose 5%, glucose 10%, Hartmann’s, sodium chloride 0.9%
Y-site: Amino acid solutions. Amiodarone, anidulafungin, atracurium, bivalirudin, caspofungin, cisatracurium, dexmedetomidine, dobutamine, dopamine, ethanol, fentanyl, glyceryl trinitrate, heparin sodium, milrinone, morphine sulfate, pancuronium, potassium chloride, ranitidine,
remifentanil, sodium nitroprusside, tigecycline, tirofiban, vecuronium.
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Incompatibility
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Fluids: Sodium bicarbonate.
Y-site: Aciclovir, aminophylline, ampicillin, atropine, azathioprine, calcium chloride, calcium gluconate, cefalotin, chloramphenicol, digoxin, ergometrine, ganciclovir, hyaluronidase,, hydrocortisone sodium succinate, indomethacin, noradrenaline, phenobarbitone sodium, sodium bicarbonate, thiopentone, vancomycin.
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Stability
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Not for dilution. Discard remainder after use.
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Storage
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Ampoule: Store below 25°C. Protect from light.
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