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Neonatal Intensive Care Drug Manual
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| bet | 26/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Maximum daily dose
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The maximum single dose is 1 mg.
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Route
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Intravenous
Intratracheal
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Preparation/Dilution
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Intravenous
Draw up 0.1–0.3 mL.kg of adrenaline 1:10,000 ampoule [1 mg/10 mL] undiluted. [1 mL contains 0.1 mg (100 microgram) of adrenaline].
Intratracheal
Draw up 0.5–1 mL.kg of adrenaline 1:10,000 ampoule [1 mg/10 mL] undiluted. [1 mL contains 0.1 mg (100 microgram) of adrenaline].
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Administration
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Intravenous
Intravenous as a rapid bolus ideally through a central venous catheter followed by a sodium chloride 0.9% flush.
Intratracheal
Intratracheally via an endotracheal tube as a single bolus. If the intratracheal dose is not effective, an intravenous dose should be administered as soon as possible.
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Monitoring
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Assessment throughout the resuscitation is based on the infant’s heart rate, breathing, tone and oxygenation. A prompt increase in heart rate remains the most sensitive indicator of resuscitation efficacy. Therefore, a rapid and reliable method of measuring the newborn’s heart rate is a critical adjunct for neonatal resuscitation. ECG is much faster and more accurate in determining HR in the delivery room compared to palpation, auscultation or use of pulse oximetry. Hence it is recommended that HR should be monitored electrocardiographically in newborns needing resuscitation. [2]
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