• Drug Interactions
  • Neonatal Intensive Care Drug Manual




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    Contraindications

    Nil.

    Precautions

    Infants with arrhythmias, hypertension or hyperthyroidism. Infants with dilated or ischaemic cardiac disease.

    Intra-arterial and intramuscular administration should be avoided as it may cause local ischaemic damage.



    Drug Interactions

    Hypotension may be observed with concurrent use of vasodilators such as glyceryl trinitrate, nitroprusside and calcium channel blockers.

    Concurrent use of digitalis glycosides may increase the risk of cardiac arrhythmias. Concurrent use of IV phenytoin with adrenaline may result in dose dependent, sudden

    hypotension and bradycardia.



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    Neonatal Intensive Care Drug Manual

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