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IV bolus, IM, oral, sublingual and intranasal
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| bet | 357/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
IV bolus, IM, oral, sublingual and intranasal
Using 5 mg/mL ampoule, draw up 0.4 mL (2000 microgram of midazolam) and add 9.6 mL of sodium chloride 0.9% to make final volume of 10 mL with a concentration of 200 microgram/mL.
Using 5 mg/5mL ampoule, draw up 1 mL (1000 microgram of midazolam) and add 4 mL of sodium chloride 0.9% to make final volume of 5 mL with a concentration of 200 microgram/mL.
Administration
IV infusion: continuous infusion via a syringe pump. Change solution every 24 hours.
IV bolus: slow push over 10 minutes.9
Oral: Plastic IV ampoules may be used for oral administration.
Intranasal: IV ampoules may be used for intranasal administration. Drop dose into alternating nostrils over 15 seconds. Absorption is rapid; maximum effect in 10 minutes and duration up to 2 hours. May be irritating to nasal mucosa.
IM: Inject deep into a large muscle.
Monitoring
Apnoea, respiratory depression
Blood pressure
Level of sedation.
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