• Precautions Ensure adequate circulating blood volume prior to commencement. Loading dose
  • Prematurity
  • Neonatal Intensive Care Drug Manual




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    Contraindications


    Severe obstructive aortic or pulmonary valvular disease or hypertrophic subaortic stenosis. Hypersensitivity to milrinone, other 3,4'-bipyridines (inamrinone) or any other ingredient of the formulation.


    Precautions

    Ensure adequate circulating blood volume prior to commencement.

    Loading dose: Considered optional depending on clinical circumstances. May cause hypotension. Monitor BP and heart rate closely and ensure adequate volume replacement.

    Prematurity: Long half-life reported (10 hours) in very preterm infants.5 Avoid prolonged higher rate infusion ≥0.2 microgram/kg/minute.


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    Neonatal Intensive Care Drug Manual

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