Neonatal Intensive Care Drug Manual




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Milrinone


Revision Date : 16-11-2020

Approved : TC, KOH




Alert

May cause hypotension. Caution advised when using loading dose.

Reduce infusion rate for infants with renal impairment and prematurity.




Indication


Inotrope and vasodilator for:

1. Treatment of low cardiac output and as an adjunct to inhaled nitric oxide in neonates with persistent pulmonary hypertension of the neonate 1.

2. Prevention of low cardiac output syndrome (LCOS) post cardiac surgery 2

3. Treatment of myocardial dysfunction in neonates and children with shock particularly in context of enteroviral 71 infection 4.




Action

Selective inhibitor of type 3 cAMP phosphodiesterase in cardiac and vascular muscle.


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Neonatal Intensive Care Drug Manual

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