|
Hypotensive preterm infants
|
| bet | 44/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
| Hypotensive preterm infants: One trial [8] with 20 infants in each group with a systolic BP <40 mmHg compared fresh frozen plasma to albumin 4.5% 15 mL/kg and reported no difference in change in mean BP, although both these groups had a significantly greater increase in mean BP than a control group who received albumin 20% 5mL/kg. Other outcomes were not reported.
Conclusion: Albumin 20% solution cannot be recommended as treatment of hypotension in newborn infants. [LOE II, GOR C]
Routine treatment of preterm infants: One study [9] randomised 25 normotensive preterm infants to routine treatment with albumin 20% 15 mL/kg (3 g/kg) or no treatment and reported no difference in mortality (RR 0.92, 95% CI 0.23, 3.72) or periventricular leukomalacia. Conclusion: Albumin 20% solution cannot be recommended as routine treatment in preterm infants. [LOE I GOR C]
|
| |
