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Neonatal Intensive Care Drug Manual
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| bet | 469/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Maximum Daily Dose
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Preparation/Dilution
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Oral
Option 1 (preferred option for infants going home or when a long storage time is required in the NICU): Disperse 500 mg (16.1 mmol) Phosphate-Sandoz in 16 mL of water for injection to make a solution with a concentration of 1 mmol/mL.
Option 2 (can be used where preparation with low osmolality is preferred e.g. infants with history of feed intolerance): IV sodium dihydrogen phosphate decanted into a bottle and given orally undiluted (expiry time: 7 days).
IV infusion for treatment of acute hypophosphataemia:
IV infusion (sodium dihydrogen phosphate): Draw up 1 mL (1 mmol phosphate) and add 19 mL sodium chloride 0.9% or glucose 5% to make a final volume of 20 mL with a concentration of 0.05 mmol/mL. Draw up 3 mL/kg (0.15 mmol/kg).
IV infusion (potassium dihydrogen phosphate): Draw up 1 mL (1 mmol phosphate) and add 24 mL sodium chloride 0.9% or glucose 5% to make a final volume of 25 mL with a concentration of 0.04 mmol/mL. Draw up 3.75 mL/kg (0.15 mmol/kg).
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