• Drug Interactions
  • Neonatal Intensive Care Drug Manual




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    Contraindications

    Hyperphosphataemia, dehydration, severe renal insufficiency, shock.

    Precautions

    Hypernatraemia (avoid sodium dihydrogen phosphate).

    Hyperkalaemia (avoid potassium dihydrogen phosphate)



    Drug Interactions

    Calcium and magnesium antacids (e.g. acetate, carbonate, citrate, hydroxide etc.) reduce phosphate absorption — separate doses by at least 2 hours.

    Additive effects with other drugs that may prolong QT interval.

    Potassium dihydrogen phosphate preparation may increase the risk of hyperkalaemia when used in conjunction with potassium sparing diuretics (e.g. spironolactone).



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    Neonatal Intensive Care Drug Manual

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