• Presentation
  • Other strengths of potassium chloride have been intentionally excluded from this neonatal formulary . Dose
  • Discuss with clinician in-charge prior to rapid IV correction of hypokalaemia. Dose and administration may be altered as the clinical condition dictates.
  • Maximum dose
  • Drug type Electrolyte. Trade name




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    Drug type

    Electrolyte.

    Trade name

    Pfizer Sterile Potassium Chloride Concentrate, Potassium Chloride Juno

    Presentation

    Baxter Potassium Chloride 10 mmol/100 mL and Sodium Chloride 0.29% solution

    Pfizer (Perth) Sterile Potassium Chloride Concentrate (Concentrate for infusion): 10 mmol/10 mL and

    Potassium Chloride Juno Concentrate: 10 mmol/10 mL.

    Other strengths of potassium chloride have been intentionally excluded from this neonatal formulary.


    Dose

    Potassium Chloride 10 mmol/100 mL can be used as side arm infusion preferably through central line.
    Mild to moderate hypokalaemia (<3.5 mmol/L) with no ECG changes

    Check if the regular maintenance IV fluid has potassium chloride in the solution.

    Maintenance IV fluid containing potassium may be adequate.
    Parenteral maintenance dose can be provided in maintenance IV fluids as:

    Not greater than 4 mmol/100 mL (20 to 40 mmol/L) of potassium chloride in peripheral IV fluids;

    Not greater than 8 mmol/100 mL (80 mmol/L) of potassium chloride in central IV fluids
    The daily parenteral maintenance dose of potassium:


    Weight

    Dose

    <1500 g

    2 to 5 mmol/kg/day

    ≥1500 g

    1.5 to 3.0 mmol/kg/day


    Severe (Serum potassium <1.5 mmol/L) or symptomatic hypokalaemia with ECG changes (2)

    Discuss with clinician in-charge prior to rapid IV correction of hypokalaemia. Dose and administration may be altered as the clinical condition dictates.

    0.3 to 0.5 mmol/kg potassium chloride diluted with 2 mL/kg of sodium chloride 0.9% over 2 to 3 hours. Do not exceed rate of 0.2 mmol/kg/hour

    Repeat dose if serum potassium level is not corrected.


    Dose adjustment


    Therapeutic hypothermia – Ensure adequate urine output and renal function.

    ECMO – Determined by renal function.

    Renal impairment – Ensure adequate urine output prior to supplementation.

    Hepatic impairment – No specific dose adjustment.



    Maximum dose





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