Neonatal Intensive Care Drug Manual

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Infusion rate
Prescribed amount
1 mL/kg/hour = 0.4 mmol/kg/hour	5 mL of sodium chloride 23.4% and make up to 50 mL of water for injection

*1 mL/kg of 0 .4 mmol/mL of sodium chloride will raise serum sodium by 0.8 mmol/L.²
Oral: To be given mixed with feeds.

Sodium chloride 23.4%: Use vials for oral dosing or oral solution supplied by pharmacy

Administration

IV:

IV infusion. Must be diluted as above prior to IV infusion.

Oral:

Sodium chloride 23.4% – to be given mixed with feeds.

Divide the daily oral dose into 3–12 doses, aiming for a small but practical volume.

Monitoring

IV: Watch the local site for signs of extravasation.

Oral: Watch for signs of gastric irritation.

Monitor serum sodium as per clinical team’s recommendation.

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