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Neonatal Intensive Care Drug Manual
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| bet | 564/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Compatibility
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IV Fluids: Glucose 5%, glucose 10%, glucose 5% in sodium chloride 0.9%, glucose 5% in sodium chloride 0.45%, sodium chloride 0.9%, sodium chloride 0.45%.
Y site: No information.
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Incompatibility
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IV Fluids: Fat emulsion.
Y site: No information.
Amino Acid solutions – No information.
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Stability
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PO: Expiry 7 days from manufacture.
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Storage
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IV: Store at room temperature, 20–25°C.
PO: Refrigerate (2–8°C).
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Osmolarity of undiluted hypertonic sodium chloride is >1000 mOsm/L, posing the risk of extravasation for peripheral IV solutions.3,4 So, local consensus was to bring the osmolarity of IV preparation to 2.4% sodium chloride that has 0.4 mmol/L of sodium and an estimated osmolarity of 855 mOsm/L.
Total body water is traditionally calculated as weight x 0.6 in children. Greater total body water content in newborns should be considered and therefore should be calculated as weight x 0.75.2,5
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