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Neonatal Intensive Care Drug Manual
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bet | 572/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
2015 ACC/AHA/HRS guidelines: There is no infant recommendation. Sotalol may be reasonable for ongoing management in patients with symptomatic SVT who are not candidates for, or prefer not to undergo, catheter ablation. (LOE II, GOR B)
Sotalol for paroxysmal SVT: In a single RCT in adults, sotalol was shown to be effective in reducing SVT recurrence and time to recurrence.2 In case series in neonates and children, paroxysmal SVT was completely or partially controlled in 80–90% of patients.3-6 (LOE IV GOR C) Sotalol has been reported in combination with flecainide for treatment of refractory SVT in children < 1 year of age.6 (LOE IV, GOR C)
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