Neonatal Intensive Care Drug Manual

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Adverse Reactions
Sotalol is usually well tolerated. The most frequent adverse events arise from its beta-blockade properties. Adverse events are usually transient in nature and include dyspnoea, fatigue, dizziness, headache, fever, excessive bradycardia and/or hypotension. These side effects usually disappear when the dose is reduced. Sotalol may be proarrhythmic with prolongation of Qtc interval. Uncommonly sotalol may be associated with torsades de pointes: Cease medication; correct electrolyte abnormalities; give magnesium 0.1–0.2 mmol/kg = 25−50 mg/kg IV.¹
Storage	Oral suspension prepared by pharmacy: Refrigerate, store at 2–8°C

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