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Neonatal Intensive Care Drug Manual
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| bet | 584/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Dosage/Interval
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IV (preferred): 2 mg/kg (up to 3 mg/kg)
IM (only if IV is not accessible): 3–4 mg/kg9 (onset of action can be delayed up to 3 minutes and duration of action is up to 15 minutes)
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Dose adjustments
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Therapeutic hypothermia: No information on the dose adjustment, but has been used.
ECMO: Not applicable.
Renal impairment: use with caution as use associated with hyperkalaemia.
Hepatic impairment: may prolong duration of action. Avoid repeated doses.
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Route
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IV, IM
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Maximum Dose
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IV: 3 mg/kg/dose; IM: 4 mg/kg/dose
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Preparation
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IV:
Dihydrate salt: Draw up 1 mL (50 mg of suxamethonium) and add 9 mL sodium chloride 0.9% to make final volume 10 mL with a concentration of 5 mg/mL.
Anhydrous salt: Draw up 0.9 mL (50 mg of suxamethonium) and add 9.1 mL sodium chloride 0.9% to make a final volume of 10 mL with concentration of 5 mg/mL.
IM: Administer undiluted.
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Administration
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IV: Rapid injection at proximal cannula site.
IM: Administer in anterior thigh muscle.
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Monitoring
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Continuous cardiorespiratory monitoring. Monitor temperature, blood pressure, oxygenation and assisted ventilator status.
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