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Neonatal Intensive Care Drug Manual
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| bet | 62/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Practice Points
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The pharmacokinetics of clavulanate has not been evaluated in neonates. Further trials are needed to establish the safety and efficacy of iv-to-oral switch therapy in neonates, although some efficacy data exist for infants >1 month age. [9] [LOE I GOR C], Amoxicillin-clavulanic acid should be considered a 2nd line agent for infants with WHO defined non-, severe community-acquired pneumonia. There are no data for infants <3 months age. [LOE I, GOR B], Amoxicillin-clavulanate should be considered a 2nd line agent for infants with a urinary tract infection, or for oral to IV switch therapy for pyelonephritis with a sensitive organism for infants >1 month age.[LOE I GOR B],
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References
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Petri WA Jr. Penicillins, cephalosporins and beta-lactam antibiotics. In Goodman and Gilman’s The Pharmacologic Basis of Therapeutics. 12th Ed. The McGrath-Hill Companies. P1477-1503.
MIMS online. Amoxicillin-clavulanic acid. Accessed on 21st October 2019.
Kucers’ The use of antibiotics. A clinical review of antibacterial, antifungal, antiparasitic andantiviral drugs. 6th ed. Grayson LM CS, McCarthy JS, Mills J, Mouton JW, Norrby SR, Paterson DL,
Pfaller PA, editor: CRC Press, Taylor & Francis Group; 2013.BNFC https://www.medicinescomplete.com.acs.hcn.com.au/#/content/bnfc/_522717287?hspl=augmen tin#DMD94411000001100
Blond MH, Gold F, Marchand S, Pierre F, Congard B, Soutoul JH, Laugier J. Orally administeredantibiotic treatment of infected neonates. A prospective study in a maternity unit. [French].
Journal de Gynecologie Obstetrique et Biologie de la Reproduction. 1990; 19:1057-60.Australian injectable drug handbook.https://aidh.hcn.com.au/browse/a/amoxicillin_sodium_with_potassium_clavulanate. Accessed on 21 October 2019.
Easton J, Noble S, Perry CM, Cuffini AM, Jacobs MR, Subba Rao SD, Pichichero ME, Thornsberry C. Amoxicillin/clavulanic acid: A review of its use in the management of paediatric patients with acute otitis media. Drugs. 2003; 63:311-40.
Huttner A, Bielicki J, Clements MN, Frimodt-Moller N, Muller AE, Paccaud JP, Mouton JW. Oral amoxicillin and amoxicillin-clavulanic acid: properties, indications and usage. Clinical Microbiology and Infection. 2020.
Keij FM, Kornelisse RF, Hartwig NG, Reiss IKM, Allegaert K, Tramper-Stranders GA. Oral antibioticsfor neonatal infections: A systematic review and meta-analysis. J Antimicrob Chemother. 2019;74:3150-61.
Magin EC, Garcia-Garcia JJ, Sert SZ, Giralt AG, Cubells CL. Efficacy of short-term intravenousantibiotic in neonates with urinary tract infection. 2007; 1:83-6.
Lodha R, Kabra SK, Pandey RM. Antibiotics for community-acquired pneumonia in children.Cochrane Database Syst Rev. 2013:CD004874.
Venekamp RP, Burton MJ, van Dongen TMA, et al. Antibiotics for otitis media with effusion in children. Cochrane Database of Systematic Reviews 2016, Issue 6. Art. No.: CD009163.
Fitzgerald A, Mori R, Lakhanpaul M, Tullus K. Antibiotics for treating lower urinary tract infection inchildren. Cochrane Database Syst Rev. 2012:CD006857.
Michael M, Hodson EM, Craig JC, Martin S, Moyer VA. Short versus standard duration oral antibiotic therapy for acute urinary tract infection in children. Cochrane Database Syst Rev. 2003:CD003966.
Sanchez UC, Balaguer A. Treatment for the urinary low tract infection. A study of 5 antibiotics. Anales Espanoles de Pediatria. 1990; 33(Suppl 41):85-6.
Strohmeier Y, Hodson EM, Willis NS, Webster AC, Craig JC. Antibiotics for acute pyelonephritis in children. Cochrane Database Syst Rev. 2014:CD003772.
Fleisher GR, Wilmott CM, Campos JM. Amoxicillin combined with clavulanic acid for the treatment of soft tissue infections in children. Antimicrob Agents Chemother. 1983; 24:679-81.
Kar PK. Use of Amoxicillin and Clavulanic Acid (Augmentin) in the Treatment of Skin and Soft Tissue Infections in Children. Med J Armed Forces India. 1997; 53:87-90.
Salvo F, De Sarro A, Caputi AP, Polimeni G. Amoxicillin and amoxicillin plus clavulanate: A safety review. Expert Opinion on Drug Safety. 2009; 8:111-8.
Lonsdale DO, Baker EH, Kipper K, Barker C, Philips B, Rhodes A, Sharland M, Standing JF. Scaling beta-lactam antimicrobial pharmacokinetics from early life to old age. British Journal of Clinical Pharmacology. 2019; 85:316-46.
Lonnerholm G, Bengtsson S, Ewald U. Oral Pivampicillin and amoxycillin in newborn infants. Scandinavian Journal of Infectious Diseases. 1982; 14:127-30.
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