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Neonatal Intensive Care Drug Manual
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| bet | 86/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Calcium Gluconate
Revision Date: 2-3-2021
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Approved : TC, KOH
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Alert
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Multiple forms of calcium exist with varying amounts of elemental calcium expressed in varying units. Therefore careful attention is required in prescription and administration of calcium to avoid over- or under-dosing.
Conversion factor for elemental Ca: 1 mg = 0.02 mmol = 0.05 mEq.
Prescribe calcium in mmol/kg/dose (not in mL/kg/dose)
Calcium can slow the heart rate and precipitate arrhythmias. In cardiac arrest, calcium may be given by rapid intravenous injection. In the presence of a spontaneous circulation give it slowly.
Do not give calcium solutions and sodium bicarbonate simultaneously by the same route to avoid precipitation.
Calcium chloride 10% may be preferred over calcium gluconate 10% for rapid IV administration.
Calcium gluconate in glass vials should not be used for repeated or prolonged treatment due to the high aluminium content.
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Indication
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Asymptomatic or symptomatic hypocalcaemia.
Hyperkalaemia.
Exchange transfusion.
Magnesium toxicity.
Calcium channel blocker overdose.
Supplementation in parenteral nutrition (beyond the scope of this guideline).
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Action
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Calcium is essential for the functional integrity of the nervous, muscular, skeletal and cardiac systems and for clotting function. It antagonises the cardiotoxic effects (arrhythmias) of hyperkalaemia, hypermagnesaemia and calcium channel blockers.
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Drug Type
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Mineral.
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Trade Name
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Calcium Gluconate Injection [Phebra] 10% injection (calcium 0.22 mmol/mL)
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Maximum Dose
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3 mmol/kg/day25
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Presentation
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Calcium gluconate 10% 10 mL vial contains 0.22 mmol/mL of elemental calcium.23
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