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Neonatal Intensive Care Drug Manual
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| bet | 135/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Contraindications
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None known
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Precautions
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Correction of acidosis, hypotension, anaemia, hypoglycaemia and hypothermia is recommended by the manufacturer prior to poractant alpha administration but this is not always possible in practice.
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Drug interactions
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Not applicable
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Adverse reactions
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Transient: Bradycardia, hypotension, endotracheal tube blockage and oxygen desaturation. These events require stopping poractant alpha administration and taking appropriate measures to alleviate the condition. After the patient is stable, dosing may proceed with appropriate monitoring. Ventilator settings may need to be adjusted post-surfactant to accommodate increased lung compliance.
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Compatibility
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Should not be mixed with any other medications or fluids.
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Incompatibility
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Not applicable
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Stability
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Vials are for single use only. DO NOT SHAKE.
Unopened, unused vials that have warmed to room temperature can be returned to refrigerated storage within 24 hours for future use. Document on the packaging the date and time the product was removed from the fridge. Notify Pharmacy Department/NICU Pharmacist if this occurs. Do not warm to room temperature and return to refrigerated storage more than once.
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Storage
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Store at 2−8°C. Protect from light.
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Excipients
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