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Neonatal Intensive Care Drug Manual
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| bet | 247/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Glucagon
Revision Date : 15-12-2020
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Approved : TC, KOH
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Alert
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Do not run through filter or TPN
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Indication
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Management of neonatal hypoglycaemia:
Refractory to intravenous glucose infusions;
When glucose infusion is unavailable.
Management of hyperinsulinaemic hypoglycaemia (e.g. congenital hyperinsulinism).
Adjunctive treatment of beta-blocker overdose.
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Action
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Stimulates hepatic gluconeogenesis and glycogenolysis. Glucagon has a positive inotropic action.
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Drug type
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Polypeptide hormone – hyperglycaemic agent
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Trade name
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GlucaGen HypoKit 1 mg/mL
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Presentation
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1 mg/mL vial.
1 unit of glucagon = 1 mg (1000 microgram) glucagon
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Dose
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IV bolus/IM/SC
200 microgram/kg/dose. Do not exceed 1 mg/dose. IV glucose is to be administered as soon as possible.
IV infusion
5–20 microgram/kg/hour.
Consider starting dose of 20 microgram/kg/hour and decrease carefully, monitoring blood glucose, until the minimum effective dose is reached.
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