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Neonatal Intensive Care Drug Manual
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| bet | 250/654 | | Sana | 03.01.2022 | | Hajmi | 1,5 Mb. | | #14803 |
Continuous IV infusion: Via syringe driver.
Monitoring
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Blood glucose concentrations, watch for rebound hypoglycaemia after cessation.
Consider cardiorespiratory and blood pressure monitoring.
Electrolytes for continuous infusion.
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Contraindications
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Phaeochromocytoma [4-6], glucagonoma.
Hypersensitivity to glucagon or any component.
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Precautions
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Hypertension.
Insulinoma: Glucagon has been used to treat hypoglycaemia caused by insulinoma. However, it should be used cautiously because of the propensity to release insulin [7].
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Drug interactions
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Drug interactions largely unreported in newborn infants.
Glucagon has a positive inotropic action which may counteract effect of beta-blockers. Beta-blockers may reduce hyperglycaemic effect of glucagon [8].
Warfarin: Increased effect of warfarin resulting in increased risk of bleeding.[9]
Indomethacin: Glucagon may lose its ability to raise blood glucose or paradoxically may even produce hypoglycaemia [7].
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