Neonatal Intensive Care Drug Manual

Concurrent use of fluconazole may result in increased plasma concentrations of omeprazole.

Concurrent use of iron may result in reduced non-heme iron bioavailability.

Dermatologic: Rash

Gastrointestinal: Increased risk of Clostridium difficile-associated diarrhea (CDAD), Abdominal pain, constipation, diarrhea, flatulence, vomiting

Respiratory: Upper respiratory infection (adults)

Other: Fever (1 to less than 2 years, 33% )
Serious

Dermatologic: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis

Endocrine: Hypomagnesaemia

Gastrointestinal: Atrophic gastritis, Clostridium difficile diarrhea, pancreatitis

Haematological: Haemolytic anaemia

Hepatic: Hepatic encephalopathy, hepatic necrosis, liver failure

Immunological: Anaphylaxis

Musculoskeletal: Fracture of bone, hip fracture, rhabdomyolysis

Renal: Acute interstitial nephritis

IV: No information.

IV reconstituted solution and diluted solution: Stable for 6 hours below 25°C. Protect from light.

Injection: Store below 25°C. Protect from light.