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Volume 1 Issue 1
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January 2024
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ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES
“Innovative World” Scientific Research Support Center www.inno-world.uz
For outcomes common to at least two studies, the summarized results are as
follows:
a) Time of healing of oral lesions: 3 days, 4 days, 6 days, and 10 days for ACV
plus honey (study 1), ACV suspension (study 2), ACV suspension plus placebo
(study 1), and placebo alone (study 2), respectively.
b) Remission of drooling: 2 days, 2 days, 4 days, and 5.5
days for ACV plus
honey (study 1), ACV suspension (study 2), ACV suspension plus placebo (study
1), and placebo alone (study 2), respectively.
c) Remission of eating difficulties: 3 days, 4 days, 7 days, and 8 days for ACV
plus honey (study 1), ACV suspension (study 2), placebo alone (study 2), and ACV
suspension plus placebo (study 1), respectively.
d) Remission of drinking difficulties: 3 days, 3 days, 6 days, and 8 days for ACV
plus honey (study 1), ACV suspension (study 2), placebo alone (study 2), and ACV
suspension plus placebo (study 1), respectively.
e) Pain scores: A statistically significant reduction was reported for all tests
(ACV plus honey; non-alcoholic chlorhexidine rinses plus Mucosyte®;
TAT + aPDT) (studies 1, 4, 5) compared to control (ACV plus placebo; non-
alcoholic chlorhexidine rinses; TAT) (studies 1, 4, 5).
Finally, the time points for re-evaluation were
not consistent among the
included studies, but the majority of studies (1, 2, and 4) scheduled the final visit
approximately 7 days after the initiation of therapies. One study (3) did not
report
the time of follow-ups, while one study (5) examined the patients
immediately after post-op and then after 2 and 4 weeks, 3 and 6 months.
